Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat

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Hepatoprotective effect of mulberry (Morus nigra) leaves extract against methotrexate induced hepatotoxicity in male albino rat

BACKGROUND Drug-induced liver injury is a major health problem that challenges not only health care professionals but also the pharmaceutical industry and drug regulatory agencies. The possible hepatoprotective effect of the administration of mulberry ethanolic extract (MUL) leaves against hepatotoxic effect of the anti-rheumatic drug, methotrexate (MTX) was evaluated in this study both vivo (u...

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Hepatoprotective effect of Rosa canina fruit extract against carbon tetrachloride induced hepatotoxicity in rat

Objective: The present study was conducted to investigate the hepatoprotective activity of hydro-ethanolic fruit extract of Rosa canina (R. canina) against carbon tetrachloride (CCl4)-induced hepatotoxicity in rats. Methods: Male Wistar albino rats were randomly divided into six groups of 8 animals of each, including control, toxic (CCl4), R. canina 250, 500, and 750 mg/kg + CCl4 and R. canina ...

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15 صفحه اول

Protective Effect of Ricinus communis Leaves Extract on Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats

       Ricinus communis Linn. (Euphorbiaceae) is a soft wooded tree widely prevalent throughout tropics regions of the world which have a warm temperature. In the Indian system of medicine, the leaves, roots and seed oil of this plant have been used for the treatment of inflammation and liver disorders for a lo...

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Evaluation of Hepatoprotective Potential of Euphorbia Prostrata Ait Extract against Chemically Induced Hepatotoxicity in Albino Mice

Hepatic diseases are serious health issues as various pharmaceuticals, xenobiotics, environmental/chemical pollutants, some natural products and dietary supplements when used in overdose have tendency to cause hepatotoxicity. Present study was aimed at investigating hepatoprotective activity of aqueous methanolic extract of Euphorbia prostrata against paracetamol and carbon tetrachloride induce...

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ژورنال

عنوان ژورنال: BMC Complementary and Alternative Medicine

سال: 2015

ISSN: 1472-6882

DOI: 10.1186/s12906-015-0744-y